Research Bioinformatician for the Neurometabolic Diseases Laboratory

REF. 26-132_SS_AP 

About the research group

The Neurometabolic Diseases Laboratory at IDIBELL, led by Prof. Aurora Pujol, is seeking a highly motivated Bioinformatician to join our multidisciplinary team. Our research combines clinical genomics, multiomics, computational biology, and experimental models to uncover the molecular basis of rare neurological diseases and accelerate the development of precision medicine.

Our laboratory has developed an internationally recognized clinical genomics platform that has achieved a diagnostic yield of over 70% in more than 600 families with rare neurological disorders through the integration of whole-exome and whole-genome sequencing, our in-house prioritization platform ClinPrior, and functional validation studies.

We integrate state-of-the-art genomics and multiomics approaches—including short- and long-read sequencing, transcriptomics, single-cell genomics, lipidomics, metabolomics, proteomics, and methylomics—to identify disease mechanisms, discover new disease genes, and develop novel therapeutic strategies. Our research also focuses on immunometabolism and the role of complex lipids in regulating innate and adaptive immune responses, with a strong emphasis on translating discoveries into clinical practice and drug repurposing. Our projects are supported by competitive national and international grants and extensive collaborations with hospitals and research networks.

About the role

As the group's Bioinformatician, you will play a central role in developing and maintaining the laboratory's computational infrastructure and supporting multiple research projects.

Your responsibilities will include:

• Developing, implementing, and maintaining reproducible bioinformatics pipelines for NGS and multiomics data.
• Analyzing and integrating WES, short- and long-read WGS, RNA-seq, single-cell RNA-seq, methylomics, proteomics, lipidomics, metabolomics, and GWAS datasets.
• Supporting genomic diagnosis through variant prioritization and interpretation.
• Contributing to the development and maintenance of our in-house platform ClinPrior.
• Integrating genomic and clinical data to identify novel disease genes, biomarkers, and therapeutic targets.
• Implementing AI- and machine learning-based approaches for genomic data analysis and clinical report generation.
• Managing genomic and clinical databases (including REDCap and SQLite) and ensuring FAIR data practices.
• Collaborating closely with clinicians, computational scientists, and experimental researchers across multiple projects.

Job requirements

Professional experience

• Experience analyzing next-generation sequencing (NGS) data. Whole-exome sequencing (WES) and/or whole-genome sequencing (WGS) data analysis.
• Experience with RNA-seq, single-cell transcriptomics, methylomics, or other multiomics technologies.
• Experience working in Linux environments.
• Experience with Git and reproducible computational workflows.

Education and training

• MSc in Bioinformatics, Computational Biology, Genomics, Computer Science, Biomedical Engineering, or a related discipline.

Technical & soft skills

• Excellent communication skills and proficiency in English.

• Strong programming skills in Python and/or R. 

Languages

• Good command of the English language

We will value, but not required

• Experience with long-read sequencing (Oxford Nanopore or PacBio).
• Knowledge of clinical genomics and variant interpretation, including databases such as gnomAD, ClinVar, OMIM, and HPO.
• Experience using HPC environments, Docker/Singularity, and cloud computing.
• Experience applying machine learning or generative AI to biomedical data analysis.
• Familiarity with workflow management systems (Nextflow, Snakemake, or equivalent).
• Interest in rare diseases and precision medicine.

What do we offer

• No. of positions: 1
• Estimated start date: 13 October 2026
•  Contract duration: Permanent
•  Estimated annual gross salary: It is commensurate with qualifications and consistent with our pay ranges.
•  You will be part of a multicultural team. We have a fun loving and friendly international work environment.
•  Flexible working schedule - We know you have a life outside of work and we will work with you to make sure it's kept that way.
•  Possibility to work some days in remote -Teleworking
•  26 working days of holiday per year
•  System of accumulated hours for employees, from 80 to 104 hours depending on the year (11 to 13 working days), to attend to personal matters.
•  Paid leave package
•  Benefits of constant training are offered
•  We offer and promote diverse and inclusive conditions. Applicants are made free from any discrimination. Specifically IDIBELL works to improve gender equality in all areas with the aim of achieving gender balance, but maintaining the most scrupulous respect to any choice at the level of gender identity. Please express yourself freely, safely and non-binarily, if that's the case.

Deadline: Please submit your application by  18/09/2026

Data protection notice

In compliance with the obligations established in the General Regulation of Data Protection (RGPD), which is the Regulation (EU) 2016/679 of the Parliament and of the Council, of April 27, 2016, and the Organic Law 3/2018, of December 5, Protection of Personal Data and guarantee of digital rights, it is reported that the Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), CIF G58863317, with address Av. Granvia de l'Hospitalet, 199-203, 08908, L'Hospitalet de Llobregat, will process your personal data, as the controller, to apply for the position, maintain communication concerning the status of the candidature, to access the delivered CV; to compare that your data is in accordance with the offers announced by IDIBELL and to verify, where appropriate, that the information provided is accurate. You can find more information in our Privacy Policy at https://idibell.cat/en/privacy-policy-2/, request more information about the data processing carried out and exercise your rights of access, rectification, deletion, opposition, portability, limitation of processing by sending a request at email: dataprotection@idibell.cat. If you consider that you have not obtained satisfaction in exercising your rights, you may submit a claim to Catalan Data Protection Authority.

Our institute

IDIBELL is a research center that integrates the biomedical research of the Bellvitge University Hospital (HUB), the Catalan Institute of Oncology (ICO), and the University of Barcelona in the Bellvitge Campus (UB), and the Viladecans Hospital (HV). The research focuses of IDIBELL are cancer, neuroscience, translational medicine and regenerative medicine. Research, innovation and society are the pivots on which researchers work every day in order to improve the quality of life of citizens.

Observations:

The 'HR Excellence in Research' award represents IDIBELL’s commitment to the implementation of Human Resources policies, which oversee the attracting and development of talent in an open, transparent, and based on personal merit, in alignment with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment Researchers (Charter and Code).

IDIBELL is committed to the principles of the Code of Conduct for the Recruitment of Researchers of the European Commission and the implementation of open, transparent and merit-based recruitment (OTMR).