Lab Technician - Hereditary Cancer
Ref.: 23-208_SS_MP
About the research group
Hereditary cancer
The selected candidate will have the opportunity to work within the Hereditary Cancer (https://idibell.cat/en/research/cancer-area/molecular-mechanisms-and-experimental-therapy-in-oncology-program-oncobell/hereditary-cancer/) and Dr. Raya's groups (https://idibell.cat/en/research/area-medicina-regenerativa-english/regenerative-medicine-program/stem-cell-potency/), under the supervision of Dr. Marta Pineda and Dr. Ángel Raya.
The overarching goal of the Hereditary Cancer group is to gain insight into the molecular basis of hereditary cancer, to personalize risk assessment to patients and relatives, as well as to individualize management regarding follow-up, treatment and prophylactic measures. One of the main research lines at Dr. Raya's group is the generation of patient-specific iPS-based models of human diseases, addressing the genetic complexity linked to increased risk or protection to suffering disease.
Successful candidate will join two dynamic, young and well-equipped research groups with strong interactions and multidisciplinary research. Both groups offer a stimulating research atmosphere and an environment in which collaboration and exchange of ideas and techniques is actively encouraged with a strong commitment to research which provides a lively and stimulating environment for young talents.
About the role
We are seeking an experienced lab technician who will develop a project aimed at identifying early events in Constitutional Mismatch Repair Deficiency (CMMRD) syndrome carcinogenesis.
CMMRD is a rare and devastating childhood-onset cancer predisposition syndrome caused by biallelic mutations in mismatch repair (MMR) genes. The spectrum of CMMRD tumors is broad being high-grade gliomas the most frequently diagnosed tumors. Accurate and prompt diagnosis is critical to intensive cancer screening and effective treatment. The severity of CMMRD is highlighted by the fact that patients do not survive until later life, emphasizing the requirement of novel tools for cancer risk surveillance and prevention in CMMRD individuals.
We aim to characterize early molecular events in CMMRD carcinogenesis to establish the basis for novel surveillance and prevention strategies. The successful candidate will be involved in the definition of the early sequential molecular events driving the formation of mismatch repair-deficient high-grade glioma by means of a human in vitro-in vivo modeling of neoplastic transformation.
Job requirements
Professional experience
Education and training
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Superior Laboratory Technician (CFGS), or Grade in biology, genetics, biochemistry, biotechnology, or related disciplines
Technical skills
Languages
We will vaue, but no required
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Proven experience in iPSCs cell culture and differentiation
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Proven experience in cell engineering, CRISPR/Cas9 technology, 2D/3D cell cultures and next-generation sequencing
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Proven knowledge in human genetics
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Master in Genetics, Genomics, regenerative medicine, biomedical sciences, or related disciplines
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Any participation in research projects, co-authorship in publications and mobility experience
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High motivation and ability to be involved in a multidisciplinary team
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High degree of work autonomy
What do we offer
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Estimated start date: 01/10/2023
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Contract duration: 12 months
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Estimated annual gross salary: 22.000 - 26.000 €
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You will be part of a multicultural team. We have a fun loving and friendly international work environment.
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Flexible working schedule - We know you have a life outside of work and we will work with you to make sure it's kept that way.
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Possibility to work some days in remote -Teleworking
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26 working days of holiday per year
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System of accumulated hours for employees, from 88 to 104 hours depending on the year (11 to 13 working days), to attend to personal matters.
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Benefits of constant training are offered
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We offer and promote diverse and inclusive conditions. Applicants are made free from any discrimination. Specifically IDIBELL works to improve gender equality in all areas with the aim of achieving gender balance, but maintaining the most scrupulous respect to any choice at the level of gender identity. Please express yourself freely, safely and non-binarily, if that's the case.
Deadline: Please submit your application by 11/09/2023
Data protection notice
In compliance with the obligations established in the General Regulation of Data Protection (RGPD), which is the Regulation (EU) 2016/679 of the Parliament and of the Council, of April 27, 2016, and the Organic Law 3/2018, of December 5, Protection of Personal Data and guarantee of digital rights, it is reported that the Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), CIF G58863317, with address Av. Granvia de l'Hospitalet, 199-203, 08908, L'Hospitalet de Llobregat, will process your personal data, as the controller, to apply for the position, maintain communication concerning the status of the candidature, to access the delivered CV; to compare that your data is in accordance with the offers announced by IDIBELL and to verify, where appropriate, that the information provided is accurate.
You can find more information in our Privacy Policy at https://idibell.cat/en/privacy-policy-2/, request more information about the data processing carried out and exercise your rights of access, rectification, deletion, opposition, portability, limitation of processing by sending a request at email: dataprotection@idibell.cat. If you consider that you have not obtained satisfaction in exercising your rights, you may submit a claim to Catalan Data Protection Authority.
Our institute
IDIBELL is a research center that integrates the biomedical research of the Bellvitge University Hospital (HUB), the Catalan Institute of Oncology (ICO), and the University of Barcelona in the Bellvitge Campus (UB), and the Viladecans Hospital (HV). The research focuses of IDIBELL are cancer, neuroscience, translational medicine and regenerative medicine. Research, innovation and society are the pivots on which researchers work every day in order to improve the quality of life of citizens.
Observations:
The 'HR Excellence in Research' award represents IDIBELL’s commitment to the implementation of Human Resources policies, which oversee the attracting and development of talent in an open, transparent, and based on personal merit, in alignment with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment Researchers (Charter and Code).
IDIBELL is committed to the principles of the Code of Conduct for the Recruitment of Researchers of the European Commission and the implementation of open, transparent and merit-based recruitment (OTMR).
The project leading to this labour contract has received funding since 1 April 2021 under the project code 202028-30.
