Researcher Assistant - Hereditary Cancer

REF: 24-136_SS_MP

About the research group

The candidate will have the opportunity to work within the DNA Mismatch Repair team of the Hereditary Cancer Group (https://hereditarycancergroup.com/team/dna-mismatch-repair-laboratory/), led by Dr. Gabriel Capellá and Marta Pineda. This group is focused on the improvement of healthcare of patients with mismatch repair associated hereditary cancer syndromes, namely Lynch syndrome and Constitutional Mismatch Repair Deficiency (CMMRD).
Successful candidates will join dynamic, young and well-equipped research group with strong interactions and multidisciplinary research. The group offers a stimulating research atmosphere for young talents and an environment in which collaboration and exchange of ideas and techniques is actively encouraged.

About the role

We are seeking an experienced Research Assistant who will develop a project aiming aimed at identifying early events in Constitutional Mismatch Repair Deficiency (CMMRD) syndrome carcinogenesis.
Constitutional mismatch repair de?ciency (CMMRD) is a rare and devastating childhood-onset cancer predisposition syndrome caused by biallelic mutations in mismatch repair (MMR) genes. The spectrum of CMMRD tumors is broad being high-grade gliomas the most frequently diagnosed tumors. Accurate and prompt diagnosis is critical to intensive cancer screening and effective treatment. The severity of CMMRD is highlighted by the fact that patients do not survive until later life, emphasizing the requirement of novel tools for cancer risk surveillance and prevention in CMMRD individuals.
We aim to characterize early molecular events in CMMRD carcinogenesis to establish the basis for novel surveillance and prevention strategies. The research assistant will be involved in the?definition of the early sequential molecular events driving the formation of mismatch repair-deficient high-grade glioma?by means of a human in vitro-in vivo modeling of neoplastic transformation.

Job requirements

Professional experience

• Proven experience in genetics and laboratory molecular techniques.

Education and training

•  CFGS in Lab Technician or similar 

Technical & soft skills

• Advanced technical skills in laboratory work.

Languages

• Good command of the English language

We will value, but not required

• Proven knowledge in human genetics, molecular biology, histology and bioinformatics.
• Experience in biological sample processing and next-generation sequencing.
• Any participation in research projects, co-authorship in publications and mobility experience will be considered as a valuable contribution.
• High motivation and ability to be involved in a multidisciplinary team.
• High degree of work autonomy.

What do we offer

•  No. of positions: 1
•  Estimated start date: 11/11/2024
•  Contract duration: Permanent linked to projects
•  Estimated annual gross salary: 22.380 €
•  You will be part of a multicultural team. We have a fun loving and friendly international work environment.
•  Flexible working schedule - We know you have a life outside of work and we will work with you to make sure it's kept that way.
•  Possibility to work some days in remote -Teleworking
•  26 working days of holiday per year
•  System of accumulated hours for employees, from 88 to 104 hours depending on the year (11 to 13 working days), to attend to personal matters.
•  Paid leave package
•  Benefits of constant training are offered
•  We offer and promote diverse and inclusive conditions. Applicants are made free from any discrimination. Specifically IDIBELL works to improve gender equality in all areas with the aim of achieving gender balance, but maintaining the most scrupulous respect to any choice at the level of gender identity. Please express yourself freely, safely and non-binarily, if that's the case.

Deadline: Please submit your application by  05/11/2024

Data protection notice

In compliance with the obligations established in the General Regulation of Data Protection (RGPD), which is the Regulation (EU) 2016/679 of the Parliament and of the Council, of April 27, 2016, and the Organic Law 3/2018, of December 5, Protection of Personal Data and guarantee of digital rights, it is reported that the Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), CIF G58863317, with address Av. Granvia de l'Hospitalet, 199-203, 08908, L'Hospitalet de Llobregat, will process your personal data, as the controller, to apply for the position, maintain communication concerning the status of the candidature, to access the delivered CV; to compare that your data is in accordance with the offers announced by IDIBELL and to verify, where appropriate, that the information provided is accurate. You can find more information in our Privacy Policy at https://idibell.cat/en/privacy-policy-2/, request more information about the data processing carried out and exercise your rights of access, rectification, deletion, opposition, portability, limitation of processing by sending a request at email: dataprotection@idibell.cat. If you consider that you have not obtained satisfaction in exercising your rights, you may submit a claim to Catalan Data Protection Authority.

Our institute

IDIBELL is a research center that integrates the biomedical research of the Bellvitge University Hospital (HUB), the Catalan Institute of Oncology (ICO), and the University of Barcelona in the Bellvitge Campus (UB), and the Viladecans Hospital (HV). The research focuses of IDIBELL are cancer, neuroscience, translational medicine and regenerative medicine. Research, innovation and society are the pivots on which researchers work every day in order to improve the quality of life of citizens.

Observations:

The 'HR Excellence in Research' award represents IDIBELL’s commitment to the implementation of Human Resources policies, which oversee the attracting and development of talent in an open, transparent, and based on personal merit, in alignment with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment Researchers (Charter and Code).

IDIBELL is committed to the principles of the Code of Conduct for the Recruitment of Researchers of the European Commission and the implementation of open, transparent and merit-based recruitment (OTMR).