Predoctoral Researcher - Hereditary Cancer
Ref: 23-207_R_MP
About the research group
Hereditary cancer
The candidate will have the opportunity to work within the Hereditary Cancer Group (https://idibell.cat/en/research/cancer-area/molecular-mechanisms-and-experimental-therapy-in-oncology-program-oncobell/hereditary-cancer/), under the supervision of Dr. Marta Pineda and Dr. Fátima Marín.
The overarching goal of the Hereditary Cancer group is to gain insight into the molecular basis of hereditary cancer, to personalize risk assessment to patients and relatives, as well as to individualize management regarding follow-up, treatment and prophylactic measures.
Successful candidate will join a dynamic, young and well-equipped research group with strong interactions and multidisciplinary research. The group offers a stimulating research atmosphere for young talents and an environment in which collaboration and exchange of ideas and techniques is actively encouraged.
About the role
Constitutional mismatch repair deficiency (CMMRD) is a rare and devastating childhood-onset cancer predisposition syndrome caused by biallelic mutations in mismatch repair (MMR) genes. The spectrum of CMMRD tumors is broad being high-grade gliomas, hematological malignancies and colorectal cancers the most frequently diagnosed tumors. Accurate and prompt diagnosis is critical to intensive cancer screening and effective treatment. The severity of CMMRD is highlighted by the fact that patients do not survive until later life, emphasizing the requirement of novel tools for cancer risk surveillance and prevention in CMMRD individuals.
The predoctoral researcher will be involved in a project aimed at improving identification and clinical management of CMMRD syndrome by:
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Performing a CMMRD screening in pediatric cancer patients by highly sensitive microsatellite instability (MSI) analysis in blood
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Evaluating the clinical utility of MSI quantification in liquid biopsy as a non-invasive tool for early detection of cancer and monitoring response to treatment
During the time in our laboratory, the selected candidate will benefit from a mentoring plan and substantial infrastructure to support his/her development. In addition, the predoctoral researcher will join the PhD program included in the Master of Biomedicine, University of Barcelona, awarded with the Quality Mention by the Ministry of Education, Spain (http://www.ub.edu/estudis/es/mastersuniversitaris/biomedicina/presentacion).
Job requirements
Professional experience
Education and training
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University degree in biology, genetics, biochemistry, biotechnology, or any related discipline
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Official Master's Degree in biomedical sciences or related disciplines
Technical skills
Languages
We will value, but not required
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Proven experience in genetics and laboratory molecular techniques
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Proven knowledge in human genetics, molecular biology and bioinformatics
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Experience in biological sample processing and next-generation sequencing
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Any participation in research projects, co-authorship in publications and mobility experience
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High motivation and ability to be involved in a multidisciplinary team
- High degree of work autonomy
What do we offer
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Estimated start date: 01/10/2023
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Contract duration: 3 years
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Estimated annual gross salary: 17.600 €
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You will be part of a multicultural team. We have a fun loving and friendly international work environment.
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Flexible working schedule - We know you have a life outside of work and we will work with you to make sure it's kept that way.
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Possibility to work some days in remote -Teleworking
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26 working days of holiday per year
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System of accumulated hours for employees, from 88 to 104 hours depending on the year (11 to 13 working days), to attend to personal matters.
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Benefits of constant training are offered
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We offer and promote diverse and inclusive conditions. Applicants are made free from any discrimination. Specifically IDIBELL works to improve gender equality in all areas with the aim of achieving gender balance, but maintaining the most scrupulous respect to any choice at the level of gender identity. Please express yourself freely, safely and non-binarily, if that's the case.
Deadline: Please submit your application by 11/09/2023
Data protection notice
In compliance with the obligations established in the General Regulation of Data Protection (RGPD), which is the Regulation (EU) 2016/679 of the Parliament and of the Council, of April 27, 2016, and the Organic Law 3/2018, of December 5, Protection of Personal Data and guarantee of digital rights, it is reported that the Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), CIF G58863317, with address Av. Granvia de l'Hospitalet, 199-203, 08908, L'Hospitalet de Llobregat, will process your personal data, as the controller, to apply for the position, maintain communication concerning the status of the candidature, to access the delivered CV; to compare that your data is in accordance with the offers announced by IDIBELL and to verify, where appropriate, that the information provided is accurate.
You can find more information in our Privacy Policy at https://idibell.cat/en/privacy-policy-2/, request more information about the data processing carried out and exercise your rights of access, rectification, deletion, opposition, portability, limitation of processing by sending a request at email: dataprotection@idibell.cat. If you consider that you have not obtained satisfaction in exercising your rights, you may submit a claim to Catalan Data Protection Authority.
Our institute
IDIBELL is a research center that integrates the biomedical research of the Bellvitge University Hospital (HUB), the Catalan Institute of Oncology (ICO), and the University of Barcelona in the Bellvitge Campus (UB), and the Viladecans Hospital (HV). The research focuses of IDIBELL are cancer, neuroscience, translational medicine and regenerative medicine. Research, innovation and society are the pivots on which researchers work every day in order to improve the quality of life of citizens.
Observations:
The 'HR Excellence in Research' award represents IDIBELL’s commitment to the implementation of Human Resources policies, which oversee the attracting and development of talent in an open, transparent, and based on personal merit, in alignment with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment Researchers (Charter and Code).
IDIBELL is committed to the principles of the Code of Conduct for the Recruitment of Researchers of the European Commission and the implementation of open, transparent and merit-based recruitment (OTMR).
The project leading to this labour contract will receive funding from 1 October 2023 under the project code AP183612023.
